Cutaneous Lymphoma in Dogs

lymphomaMy dog had a lump in the skin of his groin that became inflamed and irritated. It was removed surgically and sent for a biopsy. The result of the biopsy was cutaneous lymphoma. I know that lymphoma is a type of cancer, but I have never heard of it occurring in the skin. What should I know about this disease?

Systemic lymphoma is a very common cancer in dogs, but the cutaneous form is actually quite rare. Current statistics suggest that cutaneous lymphoma accounts for only about 5% of canine lymphoma cases.

Canine cutaneous lymphoma can present in quite a variety of lesions. The lesions can be ulcers, nodules (lumps), plaques, reddish patches, or areas of scaling and hair loss. Some dogs experience itching at the lesions. As cutaneous lymphoma progresses, the skin commonly becomes thickened, reddened, ulcerated, and may begin to ooze fluid. While any area of skin may be affected, the most common locations to find cutaneous lymphoma lesions include the junction between mucus membranes and the skin. Examples include the lip margins, the eyelids, the anus/rectum, the vulva, and the prepuce of the penis.

Cutaneous lymphoma is diagnosed via biopsy. It may spread to lymph nodes in the area of the skin lesions, which is the disease’s pathway to the rest of the body. Once the lymph nodes are involved, systemic spread to the organs can occur.

 

Is there any treatment for canine cutaneous lymphoma?

Because not very much is known about canine cutaneous lymphoma, there are no standard treatment protocols. Treatment of cutaneous lymphoma depends upon the extent of the dog’s disease. Single lesions can be removed surgically or may be treated with radiation therapy. Once the lymphoma has spread, then systemic treatment is generally recommended, which means a multi-modal chemotherapeutic approach.

 

What is the outlook for dogs with cutaneous lymphoma?

Unfortunately, canine cutaneous lymphoma typically carries with it a poor prognosis. Cutaneous lymphoma that has become systemic and is treated with a multiple chemotherapeutic agents may result in survival of 8 months to 1½ years. Overall, canine cutaneous lymphoma is a difficult and discouraging disease for both dogs and their owners.

This client information sheet is based on material written by: Robin Downing, DVM, DAAPM, DACVSMR, CVPP, CRPP

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